African Cancer Center

Foundation stone of Center was performed by His Excellency, the Governor of Lagos State, October 26, 2006

Water front views of site for the African
Cancer center- first in black Africa

AFRICAN CANCER CENTER
Lagos, Nigeria
“Curing Cancer; a Global Effort”
Proposed Building of the African Cancer Center

African Cancer Center is incorporated in the State of Texas, USA as a non-profit organization with 501© 3 status on July 20, 2006.

African Cancer Center Lay-Out

African Cancer Center Plot Survey

Board Members

Akintola Williams-Nigeria
Oye Williams-Nigeria
Chris Ogunbanjo-Nigeria
Kenneth Yellowe-USA
James Medugu-USA/Nigeria
Kunle Olumide-Nigeria
Femi Olopade-Nigeria
Philip Asiodu-Nigeria
Rep. Lagos State Government-Nigeria
Femi Okunnu-Nigeria
Rep. International Union Against Cancer, Geneva
Rep. National Cancer Institute, Bethesda, Maryland,USA
Robert C Gallo M.D.--USA
Ian Magrath M.D.-Europe
Otis Brawley M.D.-USA
Deen Olowopopo M.D.-USA
Bryant Orjiako M.D.-Nigeria
Wole Odujinrin M.D.-USA
Funmi Olopade M.D.-USA
Obinna Nwaneri M.D.-USA
Aba Sagoe M.D.-Nigeria
Clement Adebamowo M.D.- Nigeria
Tony Marinho M.D-Nigeria
Carrie Hunter M.D.-USA
J.K.Randle-Nigeria
Rep. Federal Government of Nigeria
M.F.Adeogun-Nigeria
Johnson Ekpere-Nigeria
Marie Ekpere-Nigeria
Femi Williams-USA

Members present at first ACC Board Meeting in Lagos.

Nigeria

Population: ~136,000,000
25% of population on the continent of Africa
Central location and easily accesible to 17 countries in the West Afriac sub-region
Largest share on intellectual, medial and capital $$ in the West Africa Region:
70 universities
36 university teaching hospitals.

African Cancer Center

Resources:
12 Acres (5.023 hectares) of waterfront land (worth 75 million Naira and taxes) donated by Lagos State Government for construction of center
Application for grant of international status to the center including waiver of duty on equipment to be used at the center
Pledge of 50% of equipment needed for center operation

African Cancer Center- Timeline
Building of Cancer Center
Identify Directors, Key Chairs and Committee leads
Identify key staffing personnel
Senior Leadership for each Division
Faculty needed for cancer patient care
Faculty needed for education and training
Administrative and financial operations
Maintenance of infrastructure
Developing and implementing clinical, HIV- related and translational research programs

GLOBAL BURDEN OF CANCER

Shifting from developed to developing countries

Year 2002
10.9 million new cancer cases
50% in developing countries

Year 2020
Estimated 16.5 million new cancer cases
75% will be from developing countries

Proportion of activities of the African Cancer Center shall be:

60% clinical

40% research

Population Science

Office of Prevention

Office of Training and Education

Office of Outreach and Social welfare

Partnerships with community hospitals

Medical Science
Division of Medical Oncology
Division of Surgical Oncology
Division of Radiation Therapy
Division of Anatomic & Clinical Pathology
Division of Nursing Oncology
Division of Pharmacy
Division of Diagnostic Imaging & Radiology
Office of Clinical Research

Laboratories
Hematology
Cytology and fine need aspiration
Molecular biology/Genetics
Clinical pathology
Microbiology
Parasitology
Virology
Radiology/Radiation Physicists

AIDS/HIV-Related Cancer

Africa: Estimated 29 million persons infected with HIV at end of 2001 - Represents 72.5% of the world total
AIDS-Associated Cancers
Kaposi Sarcoma- most frequently reported AIDS-associated cancer
Non-Hodgkin’s lymphoma
Cervical cancer: CIN or SIL
Ocular tumors - conjunctival

Certification and Registration

Need to recognize Oncology as a specialty by the Ministry of Health.
Need to recognize Oncology as a specialty in the post-graduate college certification.
Need to recognize Oncology as a specialty in the West African College of Surgeons and Physicians Board certification exams.
Need to recognize other diplomas in oncology for registration by Board specialties

Memberships Applied For

AU – African Union (Ethiopia)

UICC - International Union Against Cancer
(Switzerland)

INCTR - International Network Center for Training and Research (Brussels)

Proposed Corporate Sponsors

Shell
Chevron
Mobil
Exxon
Total
Agip
Conoil
African Petroleum
Texaco
Coca Cola
Nestle
Cadbury
Julius Berger
May and Baker
Globalcom
Celtell
Multilinks
Starcomms
IBTC
WAPCO
Guiness
Nigeria Breweries
Nigerian Bottling Company
Commercial Banks
Virgin Atlantic

Liver Cancer

Prevention
Prevalence of chronic infection with HBV in sub-Saharan Africa estimated to be ~11.6%
~66% of liver cancer attributed to HBV
Impact of HIV on HBV,HCV,HPV,TB,Malaria
Treatment
Few treatment options
More research is needed to evaluate new molecular entities

Breast Cancer: Risk Factors

Age – incidence increases with advancing age
Reproductive: early menarche, late menopause, few children, nulliparity, late age at first birth
Long term use of hormone replacement therapy
Lifestyle: high calorie diets, alcohol, lack of exercise
Obesity in post-menopausal women
High breast density on mammogram

Breast Cancer Incidence Rates, West Africa(Nigeria 1998-99; Gambia 1997-98; Guinea 1996-99; Mali 1988-97; Niger 1993-99) [Source: Cancer in Africa by Parkin, M. et al., 2003]

Breast Cancer

Screening mammogram
Diagnosis
Breast self-examination
Clinical examination by a physician
Diagnostic mammogram
Biopsy
Stage at diagnosis
Biological markers: ER, PgR, Her2/neu, other pathological features of the tumor

Give Tomorrow a Chance By Tackling Cancer Today.
Donner e demain unneopportunite en conmbattant le cancer aujurd 'hui.

MISSION

To provide state-of-the-art comprehensive cancer care to the people of Nigeria and West Africa

This will be accomplished by:
Improving access to treatment, prevention, and quality of care through training, cancer education, relevant research, and the creation of greater public awareness of cancer.

GOALS

Excellence in Clinical Cancer Care
Excellence in Cancer Training, Education, and Public Awareness
Excellence in Research

VISION

The African Cancer Center will be an international center of excellence and will be the premier regional center for cancer treatment, management, training, education and research in Nigeria/West Africa. It will be dedicated to improving the quality of cancer care for Nigerians and other Africans.

MANDATES:
TREATMENT
TRAINING
RESEARCH

CANCER INFORMATION
Service area: minimum 50 million population
in West African region
Cancer Center-Proposed
50-100 adult male beds
50-100 adult female beds
150 pediatric beds
Emergency Room
Day cases
Diagnostic screening

AFRICAN CANCER CENTER PRINCIPLES

Population Science
Will identify people at high risk of cancer and develop appropriate strategies to reduce these risks through programs of prevention and early detection in a low income environment
Medical Science
Will provide excellent patient care and conduct a broad-based program of clinical research
Basic Science
Will work towards understanding of both normal and abnormal cell growth and development

OFFICE OF PREVENTION
HIV/AIDS-associated cancers
Cervical cancer
Breast cancer
Liver Cancer
Prostate Cancer

AIDS/HIV-Related Cancers
Africa: Estimated 29 million persons infected with HIV at end of 2001 - Represents 72.5% of the world total
AIDS-Associated Cancers
Kaposi Sarcoma- most frequently reported AIDS-associated cancer
Non-Hodgkin’s lymphoma
Cervical cancer: CIN or SIL
Ocular tumors - conjunctival
Viral & Other Infections Account for 25% of Cancers
HPV – cervical cancer
HBV – liver (hepatocellular) cancer
HCV – liver cancer
Burkitt’s Lymphoma
Helicobacter pylori - Gastric cancer
HIV/AIDS
Malignant lymphomas
Kaposi’s sarcoma